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Monday, January 23, 2012

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Friday, January 6, 2012

Possible Cure for Leukemia Found in Fish Oil??


My Note: I caution you on the title of this press release as it is a leap from curing leukemia in mice to curing it in humans. However, this is very promising and a glimmer of hope. Human clinical trials will be starting soon, so if you or someone you know is interested, they should contact their doctor to see about getting added to the list.
Fish oil has many benefits and it would be wonderful if this could be added to its long list of health benefits, but of course more research is needed. The great part is, fish oil would not interfere with any medications being taken, allowing the patient to experience a possible successful treatment without having to stop current treatments.
I highly recommend printing this out and taking it to your doctor so he/she can look into this research further and offer to help get you in touch with the those conducting the clinical trials.
Leukemia is such a frightening disease, especially to those of us who are parents. I pray to see a cure for it, wherever it may come from, in my lifetime.
Possible Cure for Leukemia Found in Fish Oil
by Press Release : Dec 29, 2011 : Pennsylvania State University

http://www.sciencedaily.com/releases/2011/12/111222103112.htm

"We have shown that some metabolites of Omega-3 have the ability to selectively kill the leukemia-causing stem cells in mice. The important thing is that the mice were completely cured of leukemia with no relapse." -Sandeep Prabhu

NOTE FROM FOUNDING EDITOR: I'm sorry for those of you whom this discovery may be coming too late. Though it may take some time before the patent is approved, if it is granted, its value will be beyond comprehension, both in what it will accomplish and its monetary worth. -Steve Shultz

(Pennsylvania) - A compound produced from fish oil that appears to target leukemia stem cells could lead to a cure for the disease, according to Penn State researchers.

The compound - delta-12-protaglandin J3, or D12-PGJ3 - targeted and killed the stem cells of chronic myelogenous leukemia, or CML, in mice, said Sandeep Prabhu, associate professor of immunology and molecular toxicology in the Department of Veterinary and Medical Sciences. The compound is produced from EPA - Eicosapentaenoic Acid - an Omega-3 fatty acid found in fish and in fish oil, he said. (Photo: The compound shown above is D12-PGJ2, which closely resembles delta-12-protaglandin J3, or D12-PGJ3, a compound that targeted and killed the stem cells of chronic myelogenous leukemia or CML in mice. Credit: Sandeep Prabhu)

"Research in the past on fatty acids has shown the health benefits of fatty acids on cardiovascular system and brain development, particularly in infants, but we have shown that some metabolites of Omega-3 have the ability to selectively kill the leukemia-causing stem cells in mice," said Prabhu. "The important thing is that the mice were completely cured of leukemia with no relapse."

The researchers, who released their findings in the current issue of Blood, said the compound kills cancer-causing stem cells in the mice's spleen and bone marrow. Specifically, it activates a gene - p53 - in the leukemia stem cell that programs the cell's own death.
"p53 is a tumor suppressor gene that regulates the response to DNA damage and maintains genomic stability," Prabhu said.

Killing the stem cells in leukemia, a cancer of the white blood cells, is important because stem cells can divide and produce more cancer cells, as well as create more stem cells, Prabhu said.

The current therapy for CML extends the patient's life by keeping the number of leukemia cells low, but the drugs fail to completely cure the disease because they do not target leukemia stem cells, said Robert Paulson, associate professor of veterinary and biomedical sciences, who co-directed this research with Prabhu.

"The patients must take the drugs continuously," said Paulson. "If they stop, the disease relapses because the leukemia stem cells are resistant to the drugs."
Current treatments are unable to kill the leukemia stem cells, Paulson said.
"These stem cells can hide from the treatment, and a small population of stem cells give rise to more leukemia cells," said Paulson. "So, targeting the stem cells is essential if you want to cure leukemia."

During the experiments, the researchers injected each mouse with about 600 nanograms of D12-PGJ3 each day for a week. Tests showed that the mice were completely cured of the disease. The blood count was normal, and the spleen returned to normal size. The disease did not relapse.

In previous experiments, the compound also killed the stem cells of Friend Virus-induced leukemia, an experimental model for human leukemia.

The researchers focused on D12-PGJ3 because it killed the leukemia stem cells, but had the least number of side effects. The researchers currently are working to determine whether the compound can be used to treat the terminal stage of CML, referred to as Blast Crisis. There are currently no drugs available that can treat the disease when it progresses to this stage.

The researchers, who applied for a patent, are also preparing to test the compound in human trials.

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Thursday, January 5, 2012

Why Do I Take Shaklee Supplements?


Many people have asked why I take vitamin supplements and why Shaklee’s.

The reason I take vitamin supplements is because even though I try and eat right, it is nearly impossible to do. The guideline is to follow the www.choosemyplate.gov. The Choose My Plate guidelines are good to follow, but it is extremely hard to do so on an everyday basis.

Why? Well, I’m a realist. Trying to find fresh, organic whole foods in the Midwest in the middle of winter that has all the nutrients I need is virtually impossible. Even if I could, I doubt I could afford it. I try and buy fresh, organic food when I can and when it’s on sale, but I can’t do so every day. It’s just too expensive.

Then there’s the fact I admit I don’t live like a purist. I eat refined sugar, though not as much as some. I eat red meat, though again not as much as I used to.  I do try to eat right most of the time, but hey, I sometimes eat a hotdog or two with chips and a pop, too. So see, I’m not perfect and I’m not going to “preach” to you either. I just try and do the best I can and fill in the gaps with good supplementation.

I also live in the city and not on the farm. Factor in the many other reasons and that is why I take vitamin supplements. Notice that they are called “supplements”. Vitamins are designed to supplement a good diet, not replace it. You can’t eat donuts and drink pop exclusively and expect to be healthy.

Now, the reason I take Shaklee supplements is because in my opinion they are the best. No other company can match their extensive scientific testing and research. I believe no one can match their quality control measures and their high standard of manufacturing. To learn more on how Shaklee goes above and beyond check out their Health Sciences information page.

 Watch this Shaklee Difference video, and get an inside look at Shaklee product development and delivery through the eyes of the Shaklee Scientific Advisory Board, Shaklee Independent Distributors and Dr. Jaime McManus, Dr. Carsten Smidt, Cindy Latham, Les Wong, Doug Debernardi, ingredient suppliers and more. Find out why world-class athletes turn to Shaklee for top performance. 


I have come back from some pretty serious health challenges and I didn’t start to improve until I started a vitamin regimen of Shaklee’s supplements. I no longer take any pain medication and I continue to improve my health through better eating habits when I can, exercising and supplementing my diet with the best.

Everyone who has tried Shaklee’s supplements has said they noticed a dramatic improvement in their health and the way they feel. What is really great it they come with a 100% money back guarantee if the product ever fails to live up to your expectations.

When you pick Shaklee, you will know three things to be true. It is always safe. It always works. And it is always green.  That's the Shaklee Difference.

Wednesday, January 4, 2012

I Want to Lose Weight………Now!!


When it comes to weight loss how fast is fast enough for you?
In the beginning we are all “Gung Ho” aren’t we?

We make good choices about what we eat, we are exercising and we are hopeful every time we step on the scale.

But for some, like me, that number we see staring back up at us may not be going down as fast as we think it should.

For others, that number may have started out dropping fast, but has now stopped.

For some others, maybe that number hasn’t even dropped at all.

So, how fast is fast enough? I know for me, I like to see results fast, and who doesn’t, right? The hard part is watching and waiting to see the results which can take up to two weeks for some people! Ugh! It takes all the strength I have not to beat the daylights out of that scale!

How do we stay motivated when we aren’t seeing results fast enough?

One thing to remember is, you didn't put all that weight on overnight, so don't expect to lose it overnight either.

Fast weight loss rarely lasts and is really unhealthy. When you lose weight fast, it’s usually water, which means you could be de-hydrating yourself and you can also lose muscle. Losing muscle is not what you want to do. The more muscle you have the more calories you burn.

The best way to lose weight is how you put it on – one pound at a time. The average weight loss is about 2 pounds a week, give or take a pound or two.

2 pounds a week may not sound like much, but it's the surest way to keep it off.

Some weeks you will lose more and some weeks you will lose less. Women especially tend to lose weight at a slower rate than men and our weight tends to fluctuate depending on the time of the month.

So that week before your period, don’t beat yourself up too much if you see that number grow by 3-5 pounds. Just keep on what you are doing and after your period you should see a nice decrease in the scale numbers.

When it comes to weight loss, slow and steady does win the race. It may not be exciting, it can be frustrating at times, but if we shift our focus from short term to long term, then it will be easier for us to see our progress.

Remember, we put it on a pound at a time. That is exactly how we need to lose it.

Keep up the good work!

Julie

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Tuesday, January 3, 2012

Happy New Year! And some great things are coming soon!

Happy New Year Everybody!

I'm a bit belated in my wishes, but it's because I have been working on some new ideas for everyone.

We will be having some upcoming posts on easy ways to get healthier and lose weight.
Yes, it's that time of year again when many of us "Try Again" to get fit.

I, too have fallen off the wagon when it comes to losing weight and getting fit. I allowed stress, and the day to day busyness of life to creep in and wreck my schedule.
My frustration grew right along with the pounds that slowly crept back on.
If you've been there, then you know how defeated it can make you feel and how easy it is to just let things go.

But, I have a new sense of purpose, I am ready to re-start and I'm looking for others who are ready, too. I'm looking for other people who, like me, are busy beyond belief and who live in the real world.
We (let alone our families) don't eat Tofu, we don't have 3 hours a day to work out, we’re crunched for time and out of dinner ideas and we can't afford always afford a personal trainer to "whip" us into shape.
All we have is ourselves....and each other.

So let’s band together and share our goals and the things that work for us. We can also hold out a hand to a friend and hoist them back up if they fall off the wagon.

Studies have proven that those who seek out other people whose goals are the same, and they work together to achieve those goals are more successful than those who try and do it alone.

So, if you are looking for some easy ways to get healthier this year and are looking for some friends to help you through it, then come back often and see what we will have.

Please feel free to share your goals, your dreams of a better you and maybe some tips to help others who are right there with you.

If you are on Facebook, we now have a new group called "Time To Be Healthy"
This new group is open to anyone whose goal is to finally get healthy.
Whether it is to lose weight, kick a bad habit like smoking, or just get fit, this is the place to come.
You can state your goals, share what's working for you and find plenty of support.


Come Join Us!


Julie

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